About Me

Contact Information
Email:
haikuolibio@gmail.com
Address:
55 Prospect St, Yale University, New Haven, CT, 06511

My Background
My name is Haikuo Li (李海廓). I was born in Linyi, Shandong Province, China and lived there before my undergraduate.

In high school, I was most interested in mathematics and won the Bronze Medal in the Chinese Mathematics Olympics. At that point, I learned that biology had entered a big data era and required multidisciplinary approaches such as mathematical modeling and statistics to solve cutting-edge genomics problems. Therefore, I chose bioscience as my undergraduate major at Shanghai Jiao Tong University (SJTU). At SJTU, I was mainly trained in biochemistry and systems biology and led a first-author project in which we identified biomarkers for lymphoma patients with mass spectrometry-based proteomics. In my 4th year, I worked as a visiting undergraduate researcher at Yale University Department of Immunobiology to broaden my knowledge in immunology. I was awarded Shanghai Excellent Graduate in Bachelor Degree.

I started my PhD study at Washington University in St. Louis in 2019. With passion in using single-cell technologies to better precision medicine, I joined the Humphreys Lab at the Division of Nephrology. There, I developed deep expertise in both wet-lab (single-cell library generation, technology development, mouse surgery, tissue culture, microscope imaging etc.) and dry-lab skills (single-cell data preprocessing, analysis, visualization and computational modelling), and completed several first author manuscripts on single-cell technology development and applications, including two research papers published on Cell Metabolism. My thesis projects aim to identify kidney metabolic heterogeneity and decipher cellular events that drive kidney fibrosis with high-throughput single-cell multiomics approaches. We specifically selected single-cell combinatorial indexing (sci) as the platform, leveraging its unique advantage in ultra-high throughput, sample multiplexing capacity and low costs. The ultimate goal is to identify potential therapeutic targets that can be used to ameliorate kidney disease progression. I obtained my Ph.D in Molecular Genetics and Genomics in 12/2023.

I started as a postdoctoral research associate at the Fan Lab at Yale University Department of Bioengineering in 2024.

My Hobby
I love reading and writing Chinese prose/poetry in my spare time. I enjoy cooking and I am a soccer fan of Shandong Taishan FC.

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